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📢 Exciting News! Our Hydrodissection study published in renowned Journal of Surgical Research

We are thrilled to announce the publication of our groundbreaking study on the novel application of hydrodissection (HD) in laparoscopic cholecystectomy (LC) for gangrenous gallbladders (GGBs) in the esteemed Journal of Surgical Research. To our knowledge, this study represents a significant advancement in surgical techniques and offers promising results in improving surgical outcomes.


GGBs present a unique challenge in LC cases, necessitating more efficacious surgical approaches. Traditionally, blunt dissection has been the standard treatment for GGBs; however, it is associated with high iatrogenic complication rates. Our study is the first large retrospective study conducted on the use of HD in LCs for GGBs, shedding light on its potential benefits.


In this retrospective study, data from 386 LCs were meticulously collected and analyzed. Patient demographics, medical co-morbidities, operating time (OT), anesthesia time (AT), length of stay (LOS), estimated blood loss, conversion to open procedures, 30-day readmissions, and mortality were among the parameters examined.


The study categorized patients into four groups: the Vyas employing HD for GGBs (VHG), a non-Vyas group of five surgeons not employing HD for GGBs (NVG), Vyas treating non-GGBs, and a non-Vyas group of five surgeons treating non-GGBs. Control groups were age-matched and sex-matched. Statistical analysis techniques, including descriptive statistics, Mann-Whitney U testing, and chi-squared testing, were employed.


The results of our study demonstrated significantly decreased OT (P = 0.001), AT (P < 0.001), LOS (P = 0.015), and conversion to open procedures (P = 0.047) in the VHG group compared to the NVG group. HD reduced OT by an impressive 35.5% compared to blunt dissection. Although this study did not show significantly decreased estimated blood loss (P = 0.185) and 30-day readmissions (P = 0.531) between the VHG and NVG groups, the trends were promising.


The findings of our study support the association of HD with improved surgical outcomes in LCs for GGBs, as evidenced by reduced OT, AT, LOS, and conversion to open procedures. These results hold significant implications for the field of surgery, highlighting the potential of HD as a more effective approach. However, further multi-institutional studies are necessary to validate HD implementation and facilitate wider dissemination.


We are immensely grateful to the dedicated team of researchers, surgeons, and medical professionals who contributed to the success of this study. You can read our published study in the Journal of Surgical Research to gain in-depth insights into the promising benefits of hydrodissection in the treatment of gangrenous gallbladders during LC. This milestone is a testament to our ongoing dedication to innovation and improving patient outcomes.



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